Effect of Carrying out Continuous Nursing Based on Mobile Platform on the Life of Children with Leukemia after Discharge from Hospital

Objective . To analyze the e ﬀ ect of carrying out continuous nursing based on mobile platform on the life of children with leukemia after discharge. Methods . A total of 104 children diagnosed with leukemia admitted in Pediatric Internal Medicine, Hainan Provincial People ’ s Hospital, from September 2019 to August 2020 were randomly divided into two groups, observation group and control group, with 52 cases in each group. For the control group, routine follow-up was used for continuous nursing after discharge from hospital, and the observation group was treated with continuous nursing based on mobile platform on the basis of routine follow-up nursing after discharge from hospital. Results . When discharged from hospital, there was no signi ﬁ cant di ﬀ erence in SDS and SAS scores between the two groups ( P > 0 : 05 ). After 8 weeks of discharge, SDS and SAS scores in both groups were signi ﬁ cantly decreased, and SDS and SAS scores in the observation group were signi ﬁ cantly lower than those in the control group, with statistical signi ﬁ cance ( P < 0 : 05 ). After 8 weeks of discharge, the cancer-related fatigue score of the observation group was signi ﬁ cantly lower than that of the control group, and the di ﬀ erence was statistically signi ﬁ cant ( P < 0 : 05 ). When discharged from hospital, there was no signi ﬁ cant di ﬀ erence in quality of life between two groups ( P > 0 : 05 ). Eight weeks after discharge, the quality of life in both groups was signi ﬁ cantly improved, and the quality of life in the observation group was signi ﬁ cantly better than that in the control group; the di ﬀ erence was statistically signi ﬁ cant ( P < 0 : 05 ). The occurrence of adverse reactions in the observation group was signi ﬁ cantly lower than that in the control group, and the di ﬀ erence was statistically signi ﬁ cant ( P < 0 : 05 ). Conclusion . After children with leukemia were discharged from hospital, medical sta ﬀ used mobile platform to carry out continuous nursing for them, which could relieve the negative emotions of children, reduce the incidence of adverse reactions, and improve the quality of life. This kind of intervention had promotion value.


Introduction
Leukemia, commonly known as blood cancer, is mainly caused by the malignant cloning of hematopoietic stem cells in patients with cell apoptosis or the imbalance of differentiation, which belongs to a very serious malignant disease [1]. The World Health Organization's International Agency for Research on Cancer (IARC) produces global estimates for all cancers contained in the GLOBOCAN database, using data from mostly high-quality population-based cancer registries worldwide. An estimated 300,000 new cases of leukemia (2.8% of all new cancer cases) are diagnosed each year globally. It has been estimated that in Western countries, CLL constitutes the most frequent type of leukemia with 25% of cases, CML represents 20% of cases, and AML represents 20% of cases.
At present, in the treatment of children with leukemia, chemotherapy is the main treatment means, but there are many adverse reactions to chemotherapy; the treatment compliance of children is poor, causing serious negative effects on the clinical efficacy of treatment [2,3]. Under normal circumstances, the children discharged from hospital with leukemia can only be given routine discharge guidance, informing their families of discharge matters needing attention, but cannot effectively improve the resistance to treatment of the children with leukemia, unable to improve the quality of life of the children [4,5]. In children with ALL, 90% of patients achieve a complete remission, and up to 80% can remain disease free at 5 years following treatment. In adults with ALL, remissions occur in 60% to 80%, while 20% to 35% will maintain a leukemia-free survival. Leukemia is responsible for 2% to 6% of orbital tumors in children. Furthermore, up to 11% of children with proptosis will have some form of acute leukemia.
Modern nursing researchers believe that in the nursing process of children with leukemia, continuity of care is an important part of nursing care, which refers to the continuity of care after the discharge of children with leukemia [6], which involves the hospital, relatives, and the children with leukemia themselves, so that the children still get professional nursing guidance after discharge, can correct the wrong cognition of the knowledge of the disease, promote the recovery of the children, and improve the quality of life of the children [7]. Mobile platform is a common platform for modern people to socialize in recent years. It has the characteristics of real time and convenience, which is in line with the needs of modern continuous care [8]. Learning based on e-learning, being ubiquitous, allows easy access anywhere. The nursing professionals are the most important health workers that use a mobile phone for work. They use their personal mobile phones in order to acquire information and to be in contact with the rest of the health team. Mobile nursing is a platform to spread knowledge about diseases and communicate with patients about complications using mobile apps. The top advantages of using mobile devices by providers as well as patients and how they are transforming healthcare enhance physician efficiency, direct patient management, better point-of-care coordination, etc.
In order to explore the effect of carrying out continuous nursing based on mobile platform on the life of children with leukemia after discharge from hospital, 104 children with leukemia were selected and observed in this study. The report is as follows.
The rest of the article is organized according to the following pattern. Methodology is in Section 2. Section 3 discusses Results. Discussion is mentioned under Section 4, and the journal is concluded in Section 5.

General Information.
A total of 104 children diagnosed with leukemia admitted in Pediatric Internal Medicine, Hainan Provincial People's Hospital, from September 2019 to August 2020 were randomly divided into two groups, observation group and control group, with 52 cases in each group.
The following are the inclusion criteria: individuals meet the diagnostic criteria for children with leukemia that was progressively worsening anemia, early fever, unexplained bleeding, lymph node, and hepatosplenomegaly; expected survival time was greater than 2 years; the individual was in good condition and could accept follow-up work; the children and their families were informed of the study and signed the informed consent.
The following are the exclusion criteria: complicated organic disease or systemic disease; severe dysfunction of liver and kidney function; cognitive impairment or a history of mental illness; and those who voluntarily applied to withdraw from this research.
There was no statistically significant difference in general information between the two groups (P > 0:05), which are meant to be comparable. General information is shown in Table 1.

Methods.
For the control group, routine follow-up was used for continuous nursing after discharge from hospital, such as health information before transfer, regular followup, and daily attention manual distribution.
The observation group was treated with continuous nursing based on mobile platform on the basis of routine follow-up nursing after discharge from hospital: explain to children with leukemia and their families the significance, purpose, and methods of implementing continuous care based on mobile platforms before leaving the hospital; children are required to pay attention to the mobile platform inside the hospital, and the nursing staff would carry out the corresponding operation, regularly pushing knowledge about leukemia, such as the daily lifestyle and healthy diet of leukemia patients; use mobile platform to answer questions and communicate with each other; remind the children to report their condition and medication to the medical staff regularly through the mobile platform; conduct online discussions at 19:00 every night through voice and so on to encourage children to speak actively and exchange experiences and encourage children to understand other people's lifestyles, thereby improving the patient's own nursing ability [9]; answer the questions raised by the children, and remind them to return to the hospital on time; and inform children that they need to maintain good living habits in daily life to avoid a series of adverse reactions in the treatment process. For children with more problems or more serious negative emotions, personalized education and psychological intervention could be carried out through the mobile platform, and voice communication could be conducted when it was necessary to solve the difficulties of children in a timely manner. level. SDS scores are classified as normal (<50), mild depression (50 to 59), moderate to marked major depression (60 to 69), and severe to extreme major depression (>70). The raw score can be converted to an SDS Index score by multiplying the raw score times 1.25 [11]. SDS was used to evaluate the negative emotions before discharge and 8 weeks after discharge, respectively. The lower the SAS and SDS scores, the more mild the anxiety and depression, and the lesser negative emotions.
(2) Cancer-related fatigue: 8 weeks after discharge, patients in both groups were evaluated by the selfrating scale for cancer-induced fatigue [12]; the lower the score, the lesser cancer-related fatigue. (4) Occurrence of adverse reactions: the adverse reactions are oral infection, gastrointestinal reaction, perianal infection, hair loss, skin and mucosal bleeding, and hyperuricemia.

Statistical
Method. SPSS 20.0 statistical software was used for data analysis, measurement data was expressed as x ± s, and the comparison of the means between the two groups was adopted by a t test. A paired t test was used before and after intervention in the same group. Enumeration data were expressed as %, and χ 2 test was used for comparison. P < 0:05 was considered statistically significant.

Contrast Results of Negative Emotions.
When discharged from hospital, there was no significant difference in SDS and SAS scores between the two groups (P > 0:05). After 8 weeks of discharge, SDS and SAS scores in both groups were significantly decreased, and SDS and SAS scores in the observation group were significantly lower than those in the control group, with statistical significance (P < 0:05). Contrast results of negative emotions are shown in Table 2.

Contrast
Results of Cancer-Related Fatigue. After 8 weeks of discharge, the cancer-related fatigue score of the observation group was significantly lower than that of the control group, and the difference was statistically significant (P < 0:05). Contrast results of cancer-related fatigue are shown in Table 3.

Contrast Results of Quality of Life.
When discharged from hospital, there was no significant difference in quality of life between two groups (P > 0:05). Eight weeks after discharge, the quality of life in both groups was significantly improved, and the quality of life in the observation group was significantly better than that in the control group; the difference was statistically significant (P < 0:05). Contrast results of quality of life are shown in Table 4.

Contrast
Results of Occurrence of Adverse Reactions. The occurrence of adverse reactions in observation group was significantly lower than control group, and the difference was statistically significant (P < 0:05). Contrast results of occurrence of adverse reactions are shown in Table 5.

Discussion
Due to the toxic and side effects of drugs, the treatment compliance of children with leukemia is poor, and it is more difficult to strictly follow the medical advice due to the lack of continuous nursing guidance after discharge, which is very unfavorable to improve the treatment effect and prognosis [14,15]. After children with leukemia are discharged from hospital, the nursing staff will apply the mobile platform to carry out continuous nursing, which can enable the medical staff to closely combine with the patients [16], and children with leukemia lack the knowledge of disease and nursing in their daily care. By using a mobile platform, medical staff can regularly release publicity materials and the contents of the next phase of prognosis, so that children and their families can have a comprehensive understanding of the knowledge of disease and nursing [17,18]. Continuous nursing intervention can enable patients to receive continuous nursing guidance after they leave the hospital and go home. It can effectively promote patients' rehabilitation, reduce the rate of readmission, and improve the quality of life of patients [19]. Relevant studies have shown that continuous nursing guidance for children with leukemia through mobile platform can stimulate their own potential, fully mobilize their own resources, and improve their self-care ability and coping ability at home after discharge [20,21].
The results of this study showed that when discharged from hospital, there was no significant difference in SDS and SAS scores between the two groups (P > 0:05). After 8 weeks of discharge, SDS and SAS scores in both groups were significantly decreased, and SDS and SAS scores in the observation group were significantly lower than those in the control group, with statistical significance (P < 0:05). After 8 weeks of discharge, the cancer-related fatigue score of the observation group was significantly lower than that of the control group, and the difference was statistically significant (P < 0:05). When discharged from hospital, there was no significant difference in quality of life between two groups (P > 0:05). Eight weeks after discharge, the quality of life in both groups was significantly improved, and the quality of life in the observation group was significantly better than that in the control group, the difference was statistically significant (P < 0:05). The occurrence of adverse reactions in observation group was significantly lower than control group, and the difference was statistically significant (P < 0:05).

Conclusion
In conclusion, after children with leukemia were discharged from hospital, medical staff used a mobile platform to carry out continuous nursing for them, which could relieve the negative emotions of children, reduce the incidence of adverse reactions, and improve the quality of life. This kind of intervention had promotion value.

Data Availability
The data used to support the findings of this study are included within the article.

Conflicts of Interest
The authors declare that they have no conflicts of interest.